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  • Ventilation distribution during spontaneous breathing trials predicts liberation from mechanical ventilation: the VISION study

    Phoophiboon, V., et al. Critical Care. 2025

    EIT evaluated regional ventilation distribution during spontaneous breathing trials in mechanically ventilated patients. Results revealed that successfully weaned patients had a reduced ventral-to-dorsal ventilation difference, while those with higher differences were more likely to fail weaning.

  • Electrical impedance tomography monitoring in adult ICU patients:

    Scaramuzzo, G., et al. Critical Care. 2024

    This review paper is the result of an expert meeting and discusses the latest recommendations and future directions in EIT acquisition, processing, and applications during both mechanically ventilated and spontaneously breathing adult ICU patients.

  • Deciphering Mechanisms of Respiratory Fetal-to-Neonatal Transition in Very Preterm Infants

    Gaertner, V.D., et al. American Journal for Respiratory and Critical Care Medicine. 2023

    Over 10,000 breaths from 33 preterm infants (26-32 weeks GA) were analyzed with Sentec EIT to characterize breathing patterns during the transition from fetal to neonatal life: tidal breathing, braking, and holding. Findings revealed that holding breaths contributed most to early lung aeration.

  • Initial Observations on the Effect of Repeated Surfactant Dose on Lung Volume and Ventilation in Neonatal Respiratory Distress Syndrome

    Kallio, M., et al. Neonatology. 2019

    This study, part of the CRADL multicenter trial, investigated the effects of repeated surfactant dosing on regional ventilation and lung volumes in preterm infants. EIT revealed that repeated surfactant dose during invasive ventilation improved oxygenation without measurable changes in EELZ.

  • Transmission of Oscillatory Volumes into the Preterm Lung during Noninvasive High-Frequency Ventilation

    Gaertner, V.D., et al. American Journal for Respiratory and Critical Care Medicine. 2021

    This randomized crossover trial of 30 infants utilizing EIT provided the first evidence that nHFOV oscillations were effectively transmitted to the lungs, with a preference for the right and non-gravity-dependent lung regions.

  • Lung Volume Changes in Stable Preterm Infants Weaned From Nasal CPAP to High Flow

    Büchler, V.L., et al. CHEST Pulmonary. 2024.

    Monitoring preterm infants with EIT illustrated that the transition from nCPAP to high flow is likely to result in a gradual reduction in EELV, accompanied by physiological responses in heart rate and oxygenation.

  • Lung Recruitment Assessed by Electrical Impedance Tomography (RECRUIT): A Multicenter Study of COVID-19 Acute Respiratory Distress Syndrome

    Jonkman, A.H., et al. American Journal for Respiratory and Critical Care Medicine. 2023.

    In this multicenter study, EIT allowed personalized PEEP setting as a compromise between recruitability and overdistension (crossing point method) in 108 COVID-19 ARDS patients.

  • Personalized Positive End-Expiratory Pressure in Acute Respiratory Distress Syndrome: Comparison Between Optimal Distribution of Regional Ventilation and Positive Transpulmonary Pressure

    Scaramuzzo, G., et al. Critical Care Medicine. 2020.

    This study compared two methods of selecting personalized PEEP in ARDS patients: EIT based on the total amount of hypoventilated lung units ("Silent Spaces") and transpulmonary pressure (PL). EIT could guide PEEP selection based on optimal homogeneity of ventilation distribution.

  • Chest electrical impedance tomography examination, data analysis, terminology, clinical use and recommendations: consensus statement of the TRanslational EIT developmeNt stuDy group

    Frerichs, I., et al. Thorax. 2017.

    This consensus paper, prepared by the TREND group, provides consensus on clinical applications (neonatal, pediatric, and adult), unified terminology, and analysis methods for EIT. Additionally, it reviews all major work in thoracic EIT and provides recommendations for future development.

  • Imaging the Respiratory Transition at Birth: Unraveling the Complexities of the First Breaths of Life

    Tingay, D.G., et al. American Journal for Respiratory and Critical Care Medicine. 2021.

    Explored EIT as the first imaging modality to monitor the neonatal respiratory transition immediately after birth, providing insights into early lung function and potential implications for interventions in the delivery room.